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Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis
Several lines of evidence suggest a link between age-related macular degeneration and retinal cholesterol maintenance. Cytochrome P450 27A1 (CYP27A1) is a ubiquitously expressed mitochondrial sterol 27-hydroxylase that plays an important role in the metabolism of cholesterol and cholesterol-related...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408752/ https://ncbi.nlm.nih.gov/pubmed/22820291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63816 |
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