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Selective Neurodegeneration, Without Neurofibrillary Tangles, in a Mouse Model of Niemann-Pick C Disease

The BALB/c mouse model of Niemann-Pick type C (NPC) disease exhibits neuropathological similarities to the human condition. There is an age-related cerebral atrophy, demyelination of the corpus callosum, and degeneration of cerebellar Purkinje cells in the NPC mouse. In human NPC, many cortical and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: German, Dwight C., Quintero, E. Matthew, Liang, Chang-Lin, Ng, Benton, Punia, Surender, Xie, Chonglun, Dietschy, John M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2001
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408615/
https://ncbi.nlm.nih.gov/pubmed/11298365
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