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Age-related Oxidative Stress Compromises Endosomal Proteostasis
A hallmark of aging is an imbalance between production and clearance of reactive oxygen species and increased levels of oxidatively damaged biomolecules. Herein we demonstrate that splenic and nodal antigen presenting cells purified from old mice accumulate oxidatively modified proteins with side ch...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408590/ https://ncbi.nlm.nih.gov/pubmed/22840404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.06.005 |
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