The alternating conformation of analogues of poly[d(AT)].

Synthetic DNAs were prepared containing 6-methyl adenine (m6A) in place of adenine and 5-ethyl uracil (Et5U) or 5-methoxymethyl uracil (Mm5U) in place of thymine. All three modifications destabilized duplex DNAs to varying degrees. The binding of ethidium was studied to analogues of poly[d(AT)]. The...

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Main Authors: Reid, R S, Stuart, A L, Gupta, S V, Latimer, L J, Haug, B L, Lee, J S
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC340850/
https://ncbi.nlm.nih.gov/pubmed/3588295
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