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CD evidence that the alternating purine-pyrimidine sequence poly[d(A-C).d(G-T)], but not poly[d(A-T).d(A-T)], undergoes an acid-induced transition to a modified secondary conformation.

Circular dichroism and UV absorption data showed that poly[d(A-C).d(G-T)] (at 0.01M Na+ (phosphate), 20 degrees C) underwent two reversible conformational transitions upon lowering of the pH. The first transition was complete at about pH 3.9 and resulted in an acid form of the polymer that was most...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Antao, V P, Ratliff, R L, Gray, D M
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 1990
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC331167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2377455/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.14.4111
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