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Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer

Application of doxorubicin (Dox) for the treatment of cancer is restricted due to its severe side effects. We used combination strategy by combining doxorubicin (Dox) with withaferin A (WFA) to minimize the ill effects of Dox. Treatment of various epithelial ovarian cancer cell lines (A2780, A2780/C...

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Hlavní autoři: Fong, Miranda Y., Jin, Shunying, Rane, Madhavi, Singh, Raj K., Gupta, Ramesh, Kakar, Sham S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408484/
https://ncbi.nlm.nih.gov/pubmed/22860102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042265
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