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Withaferin A Synergizes the Therapeutic Effect of Doxorubicin through ROS-Mediated Autophagy in Ovarian Cancer

Application of doxorubicin (Dox) for the treatment of cancer is restricted due to its severe side effects. We used combination strategy by combining doxorubicin (Dox) with withaferin A (WFA) to minimize the ill effects of Dox. Treatment of various epithelial ovarian cancer cell lines (A2780, A2780/C...

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Библиографические подробности
Главные авторы: Fong, Miranda Y., Jin, Shunying, Rane, Madhavi, Singh, Raj K., Gupta, Ramesh, Kakar, Sham S.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408484/
https://ncbi.nlm.nih.gov/pubmed/22860102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042265
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