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Developmental Role of Zebrafish Protease-Activated Receptor 1 (PAR1) in the Cardio-Vascular System

Thrombin receptor, F2R or PAR1 is a G-protein coupled receptor, located in the membrane of endothelial cells. It has been initially found to transduce signals in hemostasis, but recently also known to act in cancer and in vascular development. Mouse embryos lacking PAR1 function die from hemorrhages...

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Bibliografiska uppgifter
Huvudupphovsmän: Ellertsdottir, Elin, Berthold, Peter R., Bouzaffour, Mohamed, Dufourcq, Pascale, Trayer, Vincent, Gauron, Carole, Vriz, Sophie, Affolter, Markus, Rampon, Christine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408399/
https://ncbi.nlm.nih.gov/pubmed/22860064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042131
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