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Developmental Role of Zebrafish Protease-Activated Receptor 1 (PAR1) in the Cardio-Vascular System

Thrombin receptor, F2R or PAR1 is a G-protein coupled receptor, located in the membrane of endothelial cells. It has been initially found to transduce signals in hemostasis, but recently also known to act in cancer and in vascular development. Mouse embryos lacking PAR1 function die from hemorrhages...

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Detalhes bibliográficos
Main Authors: Ellertsdottir, Elin, Berthold, Peter R., Bouzaffour, Mohamed, Dufourcq, Pascale, Trayer, Vincent, Gauron, Carole, Vriz, Sophie, Affolter, Markus, Rampon, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408399/
https://ncbi.nlm.nih.gov/pubmed/22860064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042131
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