Developmental Role of Zebrafish Protease-Activated Receptor 1 (PAR1) in the Cardio-Vascular System

Thrombin receptor, F2R or PAR1 is a G-protein coupled receptor, located in the membrane of endothelial cells. It has been initially found to transduce signals in hemostasis, but recently also known to act in cancer and in vascular development. Mouse embryos lacking PAR1 function die from hemorrhages...

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Библиографические подробности
Главные авторы: Ellertsdottir, Elin, Berthold, Peter R., Bouzaffour, Mohamed, Dufourcq, Pascale, Trayer, Vincent, Gauron, Carole, Vriz, Sophie, Affolter, Markus, Rampon, Christine
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408399/
https://ncbi.nlm.nih.gov/pubmed/22860064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042131
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