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AGER -429T/C Is Associated with an Increased Lung Disease Severity in Cystic Fibrosis

The clinical course of cystic fibrosis (CF) varies between patients bearing identical CFTR mutations, suggesting the involvement of modifier genes. We assessed the association of lung disease severity with the variant AGER -429 T/C, coding for RAGE, a pro-inflammatory protein, in CF patients from th...

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Detalhes bibliográficos
Main Authors: Beucher, Julie, Boëlle, Pierre-Yves, Busson, Pierre-François, Muselet-Charlier, Céline, Clement, Annick, Corvol, Harriet
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408394/
https://ncbi.nlm.nih.gov/pubmed/22860029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041913
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