Intra-coronary administration of tacrolimus markedly attenuates infarct size and preserves heart function in porcine myocardial infarction

BACKGROUND: We test the hypothesis that intra-coronary tacrolimus administration can limit infarct size and preserve left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) through ligating left anterior descending coronary artery (LAD) in mini-pigs. METHODS: Twelve male mi...

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Main Authors: Chua, Sarah, Leu, Steve, Sheu, Jiunn-Jye, Lin, Yu-Chun, Chang, Li-Teh, Kao, Ying-Hsien, Yen, Chia-Hung, Tsai, Tzu-Hsien, Chen, Yung-Lung, Chang, Hsueh-Wen, Sun, Cheuk-Kwan, Yip, Hon-Kan
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408362/
https://ncbi.nlm.nih.gov/pubmed/22658082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-9-21
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