RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling

Gliomas are the leading cause of death among adults with primary brain malignancies. Treatment for malignant gliomas remains limited, and targeted therapies have been incompletely explored. In this study, we found that the protein expression of presenilin 2 (PS2) was significantly increased in gliom...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Bei, Wang, Liang, Shen, Liang-Liang, Shen, Ming-Zhi, Guo, Xiao-Dong, Wang, Tao, Liang, Qin-Chuan, Wang, Chao, Zheng, Jun, Li, Yi, Jia, Lin-Tao, Zhang, Hua, Gao, Guo-Dong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408263/
https://ncbi.nlm.nih.gov/pubmed/22753229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos138
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