RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling

Gliomas are the leading cause of death among adults with primary brain malignancies. Treatment for malignant gliomas remains limited, and targeted therapies have been incompletely explored. In this study, we found that the protein expression of presenilin 2 (PS2) was significantly increased in gliom...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Bei, Wang, Liang, Shen, Liang-Liang, Shen, Ming-Zhi, Guo, Xiao-Dong, Wang, Tao, Liang, Qin-Chuan, Wang, Chao, Zheng, Jun, Li, Yi, Jia, Lin-Tao, Zhang, Hua, Gao, Guo-Dong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
Ämnen:
Basic and Translational Investigations
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408263/
https://ncbi.nlm.nih.gov/pubmed/22753229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos138
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