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Discovering Free Energy Basins for Macromolecular Systems via Guided Multiscale Simulation

An approach for the automated discovery of low free energy states of macromolecular systems is presented. The method does not involve delineating the entire free energy landscape but proceeds in a sequential free energy minimizing state discovery, i.e., it first discovers one low free energy state a...

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Detalles Bibliográficos
Autores principales: Sereda, Yuriy V., Singharoy, Abhishek B., Jarrold, Martin F., Ortoleva, Peter J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408247/
https://ncbi.nlm.nih.gov/pubmed/22423635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2126174
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