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Kinetic Partitioning between Synthetic and Editing Pathways in Class I Aminoacyl-tRNA Synthetases Occurs at Both Pre-transfer and Post-transfer Hydrolytic Steps

Comprehensive steady-state and transient kinetic studies of the synthetic and editing activities of Escherichia coli leucyl-tRNA synthetase (LeuRS) demonstrate that the enzyme depends almost entirely on post-transfer editing to endow the cell with specificity against incorporation of norvaline into...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cvetesic, Nevena, Perona, John J., Gruic-Sovulj, Ita
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408192/
https://ncbi.nlm.nih.gov/pubmed/22648413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.372151
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