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Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply

β-adrenergic receptors (β-ARs) promote brown adipose tissue (BAT) thermogenesis by mobilizing fatty acids and inducing the expression of oxidative genes. β-AR activation increases the expression of oxidative genes by elevating cAMP, but whether lipolytic products can modulate gene expression is not...

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Main Authors: Mottillo, Emilio P., Bloch, Ainsley E., Leff, Todd, Granneman, James G.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408177/
https://ncbi.nlm.nih.gov/pubmed/22685301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374041
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