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The Krüppel-associated Box Repressor Domain Can Induce Reversible Heterochromatization of a Mouse Locus in Vivo

The study of chromatin and its regulators is key to understanding and manipulating transcription. We previously exploited the Krüppel-associated box (KRAB) transcriptional repressor domain, present in hundreds of vertebrate-specific zinc finger proteins, to assess the effect of its binding to gene b...

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Detalhes bibliográficos
Main Authors: Groner, Anna C., Tschopp, Patrick, Challet, Ludivine, Dietrich, Jens-Erik, Verp, Sonia, Offner, Sandra, Barde, Isabelle, Rodriguez, Ivan, Hiiragi, Takashi, Trono, Didier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408170/
https://ncbi.nlm.nih.gov/pubmed/22605343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.350884
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