Streptococcal Surface Proteins Activate the Contact System and Control Its Antibacterial Activity

Group G streptococci (GGS) are important bacterial pathogens in humans. Here, we investigated the interactions between GGS and the contact system, a procoagulant and proinflammatory proteolytic cascade that, upon activation, also generates antibacterial peptides. Two surface proteins of GGS, protein...

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Hauptverfasser: Wollein Waldetoft, Kristofer, Svensson, Lisbeth, Mörgelin, Matthias, Olin, Anders I., Nitsche-Schmitz, D. Patric, Björck, Lars, Frick, Inga-Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408149/
https://ncbi.nlm.nih.gov/pubmed/22648411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373217
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