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Humanized-Single Domain Antibodies (VH/V(H)H) that Bound Specifically to Naja kaouthia Phospholipase A2 and Neutralized the Enzymatic Activity

Naja kaouthia (monocled cobra) venom contains many isoforms of secreted phospholipase A2 (sPLA(2)). The PLA(2) exerts several pharmacologic and toxic effects in the snake bitten subject, dependent or independent on the enzymatic activity. N. kaouthia venom appeared in two protein profiles, P3 and P5...

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Detalhes bibliográficos
Main Authors: Chavanayarn, Charnwit, Thanongsaksrikul, Jeeraphong, Thueng-in, Kanyarat, Bangphoomi, Kunan, Sookrung, Nitat, Chaicumpa, Wanpen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407892/
https://ncbi.nlm.nih.gov/pubmed/22852068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins4070554
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