LPA-induced suppression of periostin in human osteosarcoma cells is mediated by the LPA(1)/Egr-1 axis

Lysophosphatidic acid (LPA), a naturally occurring bioactive phospholipid, mediates a multitude of (patho)physiological events including activation of mitogen-activated protein kinases (MAPKs). As LPA may induce cellular reponses in human osteosarcoma, the present study aimed at investigating expres...

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Bibliographic Details
Main Authors: Windischhofer, Werner, Huber, Evelyn, Rossmann, Christine, Semlitsch, Michaela, Kitz, Kerstin, Rauh, Anamaria, Devaney, Trevor, Leis, Hans-Jörg, Malle, Ernst
Format: Artigo
Language:Inglês
Published: Editions Scientifiques Elsevier 2012
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407874/
https://ncbi.nlm.nih.gov/pubmed/22659570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2012.05.023
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