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Estimating the Lipophilicity of Natural Products using a Polymeric Reversed Phase HPLC Method
The integration of physicochemical profiling screens such as Log P into natural products drug discovery programs is emerging as an approach to front-load drug-like properties of natural product libraries for high-throughput screening. In this study a fast-gradient HPLC method using a polystyrene-div...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407816/ https://ncbi.nlm.nih.gov/pubmed/22851883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10826070903430464 |
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