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A new solid-phase synthesis of oligoribonucleotides by the phosphoro-p-anisidate method using tetrahydrofuranyl protection of 2'-hydroxyl groups.

Six nonaribonucleotides containing the 5'-splice site, one complementary nonamer and an octadecamer containing the 3'-splice site have been synthesized on a polymer support using the phosphoro-p-anisidate method. A 5'-linked 2'-O-tetrahydrofuranyl-N-protected nucleoside 3'-(o-chlorophenyl)phosphoro-...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Principais autores: Iwai, S, Yamada, E, Asaka, M, Hayase, Y, Inoue, H, Ohtsuka, E
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 1987
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC340780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3588309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/15.9.3761
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