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Statistical Mechanics of Transcription-Factor Binding Site Discovery Using Hidden Markov Models
Hidden Markov Models (HMMs) are a commonly used tool for inference of transcription factor (TF) binding sites from DNA sequence data. We exploit the mathematical equivalence between HMMs for TF binding and the “inverse” statistical mechanics of hard rods in a one-dimensional disordered potential to...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407691/ https://ncbi.nlm.nih.gov/pubmed/22851788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10955-010-0102-x |
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