Dysregulation of the Autophagy-Endolysosomal System in Amyotrophic Lateral Sclerosis and Related Motor Neuron Diseases

Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of incurable motor neuron diseases (MNDs) characterized by a selective loss of upper and lower motor neurons in the brain and spinal cord. Most cases of ALS are sporadic, while approximately 5–10% cases are familial. More than 16 causative...

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Библиографические подробности
Главные авторы: Otomo, Asako, Pan, Lei, Hadano, Shinji
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2012
Предметы:
Review Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407648/
https://ncbi.nlm.nih.gov/pubmed/22852081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/498428
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