Reprogrammed mouse astrocytes retain a “memory” of tissue origin and possess more tendencies for neuronal differentiation than reprogrammed mouse embryonic fibroblasts

Direct reprogramming of a variety of somatic cells with the transcription factors Oct4 (also called Pou5f1), Sox2 with either Klf4 and Myc or Lin28 and Nanog generates the induced pluripotent stem cells (iPSCs) with marker similarity to embryonic stem cells. However, the difference between iPSCs der...

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Autores principales: Tian, Changhai, Wang, Yongxiang, Sun, Lijun, Ma, Kangmu, Zheng, Jialin C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Higher Education Press 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407551/
https://ncbi.nlm.nih.gov/pubmed/21380643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1012-7
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