The paracrine effect of exogenous growth hormone alleviates dysmorphogenesis caused by tbx5 deficiency in zebrafish (Danio rerio) embryos

BACKGROUND: Dysmorphogenesis and multiple organ defects are well known in zebrafish (Danio rerio) embryos with T-box transcription factor 5 (tbx5) deficiencies, mimicking human Holt-Oram syndrome. METHODS: Using an oligonucleotide-based microarray analysis to study the expression of special genes in...

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Bibliographic Details
Main Authors: Tsai, Tzu-Chun, Lu, Jen-Kann, Choo, Sie-Lin, Yeh, Shu-Yu, Tang, Ren-Bing, Lee, Hsin-Yu, Lu, Jen-Her
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407474/
https://ncbi.nlm.nih.gov/pubmed/22776023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-63
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