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Synthesis and characterization of oligodeoxyribonucleotides containing terminal phosphates. NMR, UV spectroscopic and thermodynamic analysis of duplex formation of [d(pGGAATTCC)]2, [d(GGAATTCCp)]2 and [d(pGGAATTCCp)]2.

Derivatives of the oligomer [d(GGAATTCC)]2 with 5' (5'-P), 3' (3'-P) and both 5' and 3' (5',3'-P2) terminal phosphate groups have been synthesized and studied by temperature dependent UV and NMR spectroscopic methods. Thermodynamic studies of the helix to stra...

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Main Authors: Bower, M, Summers, M F, Kell, B, Hoskins, J, Zon, G, Wilson, W D
格式: Artigo
語言:Inglês
出版: 1987
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC340747/
https://ncbi.nlm.nih.gov/pubmed/3575099
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