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Binding of LBP-1a to Specific Immunoglobulin Switch Regions in vivo Correlates with Specific Repression of Class Switch Recombination

Upon stimulation of mature B cells, class switch recombination (CSR) can alter the specific immunoglobulin heavy chain constant region that is expressed. In a tissue culture cell line, we previously demonstrated that inhibition of late SV40 factor (LSF) family members enhanced IgM to IgA CSR. Here,...

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Detalhes bibliográficos
Main Authors: Repetny, Karen J., Zhong, Xuemei, Holodick, Nichol E., Rothstein, Thomas L., Hansen, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407417/
https://ncbi.nlm.nih.gov/pubmed/19384868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838226
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