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MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells

MAP kinase Phosphatase 3 (MKP-3) was recently identified as an important regulator of glucose homeostasis in the liver and its expression can be repressed by insulin at post transcriptional level. In this study, the mechanism underlying insulin promoted decrease of MKP-3 protein was investigated by...

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Autors principals: Feng, Bin, Jiao, Ping, Yang, Zaiqing, Xu, Haiyan
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407345/
https://ncbi.nlm.nih.gov/pubmed/22521266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.03.025
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