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MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells
MAP kinase Phosphatase 3 (MKP-3) was recently identified as an important regulator of glucose homeostasis in the liver and its expression can be repressed by insulin at post transcriptional level. In this study, the mechanism underlying insulin promoted decrease of MKP-3 protein was investigated by...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407345/ https://ncbi.nlm.nih.gov/pubmed/22521266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.03.025 |
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