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Development of a Novel In Silico Docking Simulation Model for the Fine HIV-1 Cytotoxic T Lymphocyte Epitope Mapping

INTRODUCTION: Class I HLA's polymorphism has hampered CTL epitope mapping with laborious experiments. Objectives are 1) to evaluate the novel in silico model in predicting previously reported epitopes in comparison with existing program, and 2) to apply the model to predict optimal epitopes wit...

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Detalhes bibliográficos
Main Authors: Mori, Masahiko, Matsuki, Kei, Maekawa, Tomoyuki, Tanaka, Mari, Sriwanthana, Busarawan, Yokoyama, Masaru, Ariyoshi, Koya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3407191/
https://ncbi.nlm.nih.gov/pubmed/22848572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041703
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