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Divergent Effects of Compounds on the Hydrolysis and Transpeptidation Reactions of Gamma-Glutamyl Transpeptidase
A novel class of inhibitors of the enzyme gamma-glutamyl transpeptidase (GGT) were evaluated. OU749 was shown previously to be an uncompetitive inhibitor of the GGT transpeptidation reaction. The data in this study show that it is an equally potent uncompetitive inhibitor of the hydrolysis reaction,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3407035/ https://ncbi.nlm.nih.gov/pubmed/21864033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/14756366.2011.597748 |
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