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Enhancer identification in mouse embryonic stem cells using integrative modeling of chromatin and genomic features

BACKGROUND: Epigenetic modifications, transcription factor (TF) availability and differences in chromatin folding influence how the genome is interpreted by the transcriptional machinery responsible for gene expression. Enhancers buried in non-coding regions are found to be associated with significa...

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Detalhes bibliográficos
Main Authors: Chen, Chih-yu, Morris, Quaid, Mitchell, Jennifer A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406964/
https://ncbi.nlm.nih.gov/pubmed/22537144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-152
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