ATOH7 mutations cause autosomal recessive persistent hyperplasia of the primary vitreous

The vertebrate basic helix–loop–helix (bHLH) transcription factor ATOH7 (Math5) is specifically expressed in the embryonic neural retina and is required for the genesis of retinal ganglion cells (RGCs) and optic nerves. In Atoh7 mutant mice, the absence of trophic factors secreted by RGCs prevents t...

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Detalhes bibliográficos
Main Authors: Prasov, Lev, Masud, Tehmina, Khaliq, Shagufta, Mehdi, S. Qasim, Abid, Aiysha, Oliver, Edward R., Silva, Eduardo D., Lewanda, Amy, Brodsky, Michael C., Borchert, Mark, Kelberman, Daniel, Sowden, Jane C., Dattani, Mehul T., Glaser, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406761/
https://ncbi.nlm.nih.gov/pubmed/22645276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds197
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