GFAP-Cre-Mediated Activation of Oncogenic K-ras Results in Expansion of the Subventricular Zone and Infiltrating Glioma

A subset of neoplastic cells within human high-grade gliomas has features associated with stem cells. These cells may sustain glioma growth, and their stem-like properties may confer resistance to standard glioma treatments. Whether glioma stem cells derive from indigenous neural stem cells (NSC), o...

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Autori principali: Abel, Ty W., Clark, Cara, Bierie, Brian, Chytil, Anna, Aakre, Mary, Gorska, Agnieszka, Moses, Harold L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406747/
https://ncbi.nlm.nih.gov/pubmed/19435821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-08-0477
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