Structural Mechanism of ATP-induced Polymerization of the Partition Factor ParF: IMPLICATIONS FOR DNA SEGREGATION

Segregation of the bacterial multidrug resistance plasmid TP228 requires the centromere-binding protein ParG, the parH centromere, and the Walker box ATPase ParF. The cycling of ParF between ADP- and ATP-bound states drives TP228 partition; ATP binding stimulates ParF polymerization, which is essent...

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Detalhes bibliográficos
Main Authors: Schumacher, Maria A., Ye, Qiaozhen, Barge, Madhuri T., Zampini, Massimiliano, Barillà, Daniela, Hayes, Finbarr
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406698/
https://ncbi.nlm.nih.gov/pubmed/22674577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.373696
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