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Conjugation of Glutathione to Oxidized Tyrosine Residues in Peptides and Proteins
Tyrosine residues are sensitive to oxidation and can be converted to hydroperoxides either by superoxide reacting with the Tyr radical or by singlet oxygen. These hydroperoxides rearrange to bicyclic derivatives that are readily reduced to more stable hydroxides. The aromatic character of tyrosine i...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406690/ https://ncbi.nlm.nih.gov/pubmed/22648418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371690 |
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