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Structural characterization of the voltage sensor domain and voltage-gated K(+)- channel proteins vectorially-oriented within a single bilayer membrane at the solid/vapor and solid/liquid interfaces via neutron interferometry

The voltage-sensor domain (VSD) is a modular 4-helix bundle component that confers voltage sensitivity to voltage-gated cation channels in biological membranes. Despite extensive biophysical studies and the recent availability of x-ray crystal structures for a few voltage-gated potassium (Kv-) chann...

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Main Authors: Gupta, S., Dura, J.A., Freites, J.A., Tobias, D.J., Blasie, J. K.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406608/
https://ncbi.nlm.nih.gov/pubmed/22686684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la301219z
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