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Structural characterization of the voltage sensor domain and voltage-gated K(+)- channel proteins vectorially-oriented within a single bilayer membrane at the solid/vapor and solid/liquid interfaces via neutron interferometry
The voltage-sensor domain (VSD) is a modular 4-helix bundle component that confers voltage sensitivity to voltage-gated cation channels in biological membranes. Despite extensive biophysical studies and the recent availability of x-ray crystal structures for a few voltage-gated potassium (Kv-) chann...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2012
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406608/ https://ncbi.nlm.nih.gov/pubmed/22686684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la301219z |
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