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(−)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent
We have recently found that (−)lentiginosine, a synthetic iminosugar exerting glucosidase inhibitory activity, but not its natural enantiomer lentiginosine, is endowed with an unexpected, pro-apoptotic activity. Here, we investigated mechanisms involved in apoptosis induced by −)lentiginosine in M...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406596/ https://ncbi.nlm.nih.gov/pubmed/22833097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.97 |
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