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Alpha-synuclein: from secretion to dysfunction and death

The aggregation, deposition, and dysfunction of alpha-synuclein (aSyn) are common events in neurodegenerative disorders known as synucleinopathies. These include Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. A growing body of knowledge on the biology of aSyn is em...

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Detalhes bibliográficos
Main Authors: Marques, O, Outeiro, T F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406593/
https://ncbi.nlm.nih.gov/pubmed/22825468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.94
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