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Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies

The accumulation of misfolded alpha-synuclein (aSyn) throughout the brain, as Lewy pathology, is a phenomenon central to Parkinson’s disease (PD) pathogenesis. The stereotypical distribution and evolution of the pathology during disease is often attributed to the cell-to-cell transmission of aSyn be...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Brás, Inês C., Outeiro, Tiago F.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917664/
https://ncbi.nlm.nih.gov/pubmed/33673034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10020375
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