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Influence of point mutations on the stability, dimerization, and oligomerization of human cystatin C and its L68Q variant
Human cystatin C (hCC) is a small but very intriguing protein. Produced by all nucleated cells is found in almost all tissues and body fluids where, at physiological conditions, plays a role of a very potent inhibitor of cysteine proteases. Biologically active hCC is a monomeric protein but during c...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3406405/ https://ncbi.nlm.nih.gov/pubmed/22866027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2012.00082 |
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