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Macrophage migration inhibitory factor deficiency protects pancreatic islets from cytokine-induced apoptosis in vitro

During pathogenesis of diabetes, pancreatic islets are exposed to high levels of cytokines and other inflammatory mediators that induce deterioration of insulin-producing beta cells. Macrophage migration inhibitory factor (MIF) plays a key role in the onset and development of several immunoinflammat...

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Библиографические подробности
Главные авторы: Stojanovic, I, Saksida, T, Nikolic, I, Nicoletti, F, Stosic-Grujicic, S
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406375/
https://ncbi.nlm.nih.gov/pubmed/22774990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2012.04607.x
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