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Altered Death Receptor Signaling Promotes Epithelial-to-Mesenchymal Transition and Acquired Chemoresistance

Altered death receptor signaling and resistance to subsequent apoptosis is an important clinical resistance mechanism. Here, we investigated the role of death receptor resistance in breast cancer progression. Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MCF7 breast cancer...

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Detalhes bibliográficos
Main Authors: Antoon, James W., Lai, Rongye, Struckhoff, Amanda P., Nitschke, Ashley M., Elliott, Steven, Martin, Elizabeth C., Rhodes, Lyndsay V., Yoon, Nam Seung, Salvo, Virgilio A., Shan, Bin, Beckman, Barbara S., Nephew, Kenneth P., Burow, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406343/
https://ncbi.nlm.nih.gov/pubmed/22844580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00539
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