Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro

Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain their undifferentiated state. In this study, we found significant growth inhibition of mouse ESCs (mESCs) cultured on...

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Detalhes bibliográficos
Main Authors: Kim, Gu-Hee, Lee, Gong-Rak, Choi, Hyung-Im, Park, Neung-Hwa, Chung, Hun Taeg, Han, In-Seob
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406291/
https://ncbi.nlm.nih.gov/pubmed/22595769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.7.052
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