Platelets Induce Apoptosis during Sepsis in a Contact-Dependent Manner That Is Inhibited by GPIIb/IIIa Blockade

PURPOSE: End-organ apoptosis is well-described in progressive sepsis and Multiple Organ Dysfunction Syndrome (MODS), especially where platelets accumulate (e.g. spleen and lung). We previously reported an acute sepsis-induced cytotoxic platelet phenotype expressing serine protease granzyme B. We now...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sharron, Matthew, Hoptay, Claire E., Wiles, Andrew A., Garvin, Lindsay M., Geha, Mayya, Benton, Angela S., Nagaraju, Kanneboyina, Freishtat, Robert J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406039/
https://ncbi.nlm.nih.gov/pubmed/22844498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041549
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