Irinotecan (CPT-11) Chemotherapy Alters Intestinal Microbiota in Tumour Bearing Rats

Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota changes d...

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Detalhes bibliográficos
Main Authors: Lin, Xiaoxi B., Dieleman, Levinus A., Ketabi, Ali, Bibova, Ilona, Sawyer, Michael B., Xue, Hongyu, Field, Catherine J., Baracos, Vickie E., Gänzle, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406026/
https://ncbi.nlm.nih.gov/pubmed/22844397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039764
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