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Mechanism involved in the modulation of photoreceptor-specific cyclic nucleotidegated channel by the tyrosine kinase adapter protein Grb14

We recently found that growth factor receptor-bound (Grb) protein 14 is a novel physiological modulator of photoreceptor specific cyclic nucleotide-gated channel alpha subunit (CNGA1). Grb14 promotes the CNG channel closure through its Ras-associating (RA) domain. In the current study we show that t...

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Bibliographic Details
Main Authors: Gupta, Vivek K., Rajala, Ammaji, Rodgers, Karla K., Rajala, Raju V. S.
Format: Artigo
Language:Inglês
Published: Higher Education Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405905/
https://ncbi.nlm.nih.gov/pubmed/22180090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-011-1115-1
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