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Complement Activation and Toll-Like Receptor-2 Signaling Contribute to Cytokine Production After Renal Ischemia/Reperfusion

The innate immune system causes tissue inflammation and injury after renal ischemia/reperfusion (I/R). The complement system is activated on ischemic tubular epithelial cells (TECs) and induces the cells to produce pro-inflammatory chemokines. TECs also express toll-like receptors (TLRs) -2 and -4....

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Detalhes bibliográficos
Main Authors: Amura, Claudia R., Renner, Brandon, Lyubchenko, Taras, Faubel, Sarah, Simonian, Philip L., Thurman, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405836/
https://ncbi.nlm.nih.gov/pubmed/22750071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2012.05.020
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