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A model study directed towards the preparation of nucleopeptides via H-phosphonate intermediates.

The monofunctional phosphitylating reagents bis-(N,N-diethylamino)chlorophosphine and salicylchlorophosphine have been applied for the preparation of H-phosphonates of the amino acids serine, threonine and tyrosine. Experimental evidence showed that the latter reagent was less effective for the synt...

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Autors principals: Kuyl-Yeheskiely, E, Tromp, C M, Schaeffer, A H, van der Marel, G A, van Boom, J H
Format: Artigo
Idioma:Inglês
Publicat: 1987
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC340583/
https://ncbi.nlm.nih.gov/pubmed/3103103
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